Nazanin is a sophomore studying microbiology with a minor in chemistry. She enjoys helping people, being outdoors and social, meditating, watching movies, music, dancing, and trying different cultural foods and events. She is also very interested in getting to know people from other cultures and learning new languages. She currently works on the Alzheimer’s disease (AD) and longevity project. Her research focuses on understanding how mitochondrial morphology and autophagy rates differ across ApoE mice genotypes in AD and the effects of potential therapeutic agents. She addresses this gap by using transmission electron microscopy (TEM) to document ultrastructural changes in mitochondrial cristae organization, length, and autophagy rates in ApoE4, ApoE3, and ApoE2 mice. Additionally, her study will analyze the impact of interventions on AD markers and the ultrastructural evolution of AD in these models, providing crucial tests of the mitochondrial quality hypothesis. Her long-term goal is to develop targeted therapeutic strategies that mitigate AD progression by enhancing mitochondrial health and autophagy.
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