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Publications

Click here to view Dr. Brandon Gassaway's complete Curriculum Vitae.
A complete publication list may also be viewed here.

23. Kurmi K, Liang D, van de Ven R, Georgiev P, Gassaway BM, Han S, Notarangelo G, Harris IS, Yao CH, Park JS, Hu SH, Peng J, Drijvers JM, Boswell S, Sokolov A, Dougan SK, Sorger PK, Gygi SP, Sharpe AH, Haigis MC. Metabolic modulation of mitochondrial mass during CD4(+) T cell activation. Cell Chem Biol. 2023 Sep 21;30(9):1064-1075.e8. doi: 10.1016/j.chembiol.2023.08.008. PubMed PMID: 37716347; PubMed Central PMCID: PMC10604707.

22. Naulé L, Mancini A, Pereira SA, Gassaway BM, Lydeard JR, Magnotto JC, Kim HK, Liang J, Matos C, Gygi SP, Merkle FT, Carroll RS, Abreu AP, Kaiser UB. MKRN3 inhibits puberty onset via interaction with IGF2BP1 and regulation of hypothalamic plasticity. JCI Insight. 2023 Apr 24;8(8). doi: 10.1172/jci.insight.164178. PubMed PMID: 37092553; PubMed Central PMCID: PMC10243807.

21. Gassaway BM, Li J, Rad R, Mintseris J, Mohler K, Levy T, Aguiar M, Beausoleil SA, Paulo JA, Rinehart J, Huttlin EL, Gygi SP. A multi-purpose, regenerable, proteome-scale, human phosphoserine resource for phosphoproteomics. Nat Methods. 2022 Nov;19(11):1371-1375. doi: 10.1038/s41592-022-01638-5. Epub 2022 Oct 24. PubMed PMID: 36280721; PubMed Central PMCID: PMC9847208.

20. Ferguson CJ, Urso O, Bodrug T, Gassaway BM, Watson ER, Prabu JR, Lara-Gonzalez P, Martinez-Chacin RC, Wu DY, Brigatti KW, Puffenberger EG, Taylor CM, Haas-Givler B, Jinks RN, Strauss KA, Desai A, Gabel HW, Gygi SP, Schulman BA, Brown NG, Bonni A. APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain. Mol Cell. 2022 Jan 6;82(1):90-105.e13. doi: 10.1016/j.molcel.2021.11.031. Epub 2021 Dec 22. PubMed PMID: 34942119; PubMed Central PMCID: PMC8741739.

19. Apostolidi M, Vathiotis IA, Muthusamy V, Gaule P, Gassaway BM, Rimm DL, Rinehart J. Targeting Pyruvate Kinase M2 Phosphorylation Reverses Aggressive Cancer Phenotypes. Cancer Res. 2021 Aug 15;81(16):4346-4359. doi: 10.1158/0008-5472.CAN-20-4190. Epub 2021 Jun 21. PubMed PMID: 34185676; PubMed Central PMCID: PMC8373815.

18. Huttlin EL, Bruckner RJ, Navarrete-Perea J, Cannon JR, Baltier K, Gebreab F, Gygi MP, Thornock A, Zarraga G, Tam S, Szpyt J, Gassaway BM, Panov A, Parzen H, Fu S, Golbazi A, Maenpaa E, Stricker K, Guha Thakurta S, Zhang T, Rad R, Pan J, Nusinow DP, Paulo JA, Schweppe DK, Vaites LP, Harper JW, Gygi SP. Dual proteome-scale networks reveal cell-specific remodeling of the human interactome. Cell. 2021 May 27;184(11):3022-3040.e28. doi: 10.1016/j.cell.2021.04.011. Epub 2021 May 6. PubMed PMID: 33961781; PubMed Central PMCID: PMC8165030.

17. Gassaway BM, Paulo JA, Gygi SP. Categorization of Phosphorylation Site Behavior during the Diauxic Shift in Saccharomyces cerevisiae. J Proteome Res. 2021 May 7;20(5):2487-2496. doi: 10.1021/acs.jproteome.0c00943. Epub 2021 Feb 25. PubMed PMID: 33630598; PubMed Central PMCID: PMC8210948.

16. Ringel AE, Drijvers JM, Baker GJ, Catozzi A, García-Cañaveras JC, Gassaway BM, Miller BC, Juneja VR, Nguyen TH, Joshi S, Yao CH, Yoon H, Sage PT, LaFleur MW, Trombley JD, Jacobson CA, Maliga Z, Gygi SP, Sorger PK, Rabinowitz JD, Sharpe AH, Haigis MC. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. 2020 Dec 23;183(7):1848-1866.e26. doi: 10.1016/j.cell.2020.11.009. Epub 2020 Dec 9. PubMed PMID: 33301708; PubMed Central PMCID: PMC8064125.

15. Wu J, Rowart P, Jouret F, Gassaway BM, Rajendran V, Rinehart J, Caplan MJ. Mechanisms involved in AMPK-mediated deposition of tight junction components to the plasma membrane. Am J Physiol Cell Physiol. 2020 Mar 1;318(3):C486-C501. doi: 10.1152/ajpcell.00422.2019. Epub 2020 Jan 8. PubMed PMID: 31913699; PubMed Central PMCID: PMC7099514.

14. Gassaway BM, Cardone RL, Padyana AK, Petersen MC, Judd ET, Hayes S, Tong S, Barber KW, Apostolidi M, Abulizi A, Sheetz JB, Kshitiz, Aerni HR, Gross S, Kung C, Samuel VT, Shulman GI, Kibbey RG, Rinehart J. Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production. Cell Rep. 2019 Dec 10;29(11):3394-3404.e9. doi: 10.1016/j.celrep.2019.11.009. PubMed PMID: 31825824; PubMed Central PMCID: PMC6951436.

13. Samuel VT, Petersen MC, Gassaway BM, Vatner DF, Rinehart J, Shulman GI. Considering the Links Between Nonalcoholic Fatty Liver Disease and Insulin Resistance: Revisiting the Role of Protein Kinase C ε. Hepatology. 2019 Dec;70(6):2217-2220. doi: 10.1002/hep.30829. Epub 2019 Aug 23. PubMed PMID: 31220350.

12. Codina A, Renauer PA, Wang G, Chow RD, Park JJ, Ye H, Zhang K, Dong MB, Gassaway B, Ye L, Errami Y, Shen L, Chang A, Jain D, Herbst RS, Bosenberg M, Rinehart J, Fan R, Chen S. Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity In Vivo. Cell Syst. 2019 Feb 27;8(2):136-151.e7. doi: 10.1016/j.cels.2019.01.004. Epub 2019 Feb 20. PubMed PMID: 30797773; PubMed Central PMCID: PMC6592847.

11. Gassaway BM, Petersen MC, Surovtseva YV, Barber KW, Sheetz JB, Aerni HR, Merkel JS, Samuel VT, Shulman GI, Rinehart J. PKCε contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8996-E9005. doi: 10.1073/pnas.1804379115. Epub 2018 Sep 4. PubMed PMID: 30181290; PubMed Central PMCID: PMC6156646.

10. Mohler K, Aerni HR, Gassaway B, Ling J, Ibba M, Rinehart J. MS-READ: Quantitative measurement of amino acid incorporation. Biochim Biophys Acta Gen Subj. 2017 Nov;1861(11 Pt B):3081-3088. doi: 10.1016/j.bbagen.2017.01.025. Epub 2017 Jan 24. PubMed PMID: 28130155; PubMed Central PMCID: PMC5524608.

9. D'Lima NG, Khitun A, Rosenbloom AD, Yuan P, Gassaway BM, Barber KW, Rinehart J, Slavoff SA. Comparative Proteomics Enables Identification of Nonannotated Cold Shock Proteins in E. coli. J Proteome Res. 2017 Oct 6;16(10):3722-3731. doi: 10.1021/acs.jproteome.7b00419. Epub 2017 Sep 19. PubMed PMID: 28861998; PubMed Central PMCID: PMC5647875.

8. Mohler K, Mann R, Bullwinkle TJ, Hopkins K, Hwang L, Reynolds NM, Gassaway B, Aerni HR, Rinehart J, Polymenis M, Faull K, Ibba M. Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in Saccharomyces cerevisiae. Nucleic Acids Res. 2017 Apr 20;45(7):3985-3996. doi: 10.1093/nar/gkx077. PubMed PMID: 28168297; PubMed Central PMCID: PMC5397148.

7. Petersen MC, Madiraju AK, Gassaway BM, Marcel M, Nasiri AR, Butrico G, Marcucci MJ, Zhang D, Abulizi A, Zhang XM, Philbrick W, Hubbard SR, Jurczak MJ, Samuel VT, Rinehart J, Shulman GI. Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance. J Clin Invest. 2016 Nov 1;126(11):4361-4371. doi: 10.1172/JCI86013. Epub 2016 Oct 17. PubMed PMID: 27760050; PubMed Central PMCID: PMC5096902.

6. Ferdaus MZ, Barber KW, López-Cayuqueo KI, Terker AS, Argaiz ER, Gassaway BM, Chambrey R, Gamba G, Rinehart J, McCormick JA. SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule. J Physiol. 2016 Sep 1;594(17):4945-66. doi: 10.1113/JP272311. Epub 2016 May 29. PubMed PMID: 27068441; PubMed Central PMCID: PMC5009767.

5. Rovner AJ, Haimovich AD, Katz SR, Li Z, Grome MW, Gassaway BM, Amiram M, Patel JR, Gallagher RR, Rinehart J, Isaacs FJ. Corrigendum: Recoded organisms engineered to depend on synthetic amino acids. Nature. 2015 Nov 12;527(7577):264. doi: 10.1038/nature15537. Epub 2015 Sep 23. PubMed PMID: 26416756.

4. Rovner AJ, Haimovich AD, Katz SR, Li Z, Grome MW, Gassaway BM, Amiram M, Patel JR, Gallagher RR, Rinehart J, Isaacs FJ. Recoded organisms engineered to depend on synthetic amino acids. Nature. 2015 Feb 5;518(7537):89-93. doi: 10.1038/nature14095. Epub 2015 Jan 21. PubMed PMID: 25607356; PubMed Central PMCID: PMC4590768.

3. Sawyer N, Gassaway BM, Haimovich AD, Isaacs FJ, Rinehart J, Regan L. Designed phosphoprotein recognition in Escherichia coli. ACS Chem Biol. 2014 Nov 21;9(11):2502-7. doi: 10.1021/cb500658w. Epub 2014 Oct 6. PubMed PMID: 25272187; PubMed Central PMCID: PMC4245168.

2. Löffler MG, Birkenfeld AL, Philbrick KM, Belman JP, Habtemichael EN, Booth CJ, Castorena CM, Choi CS, Jornayvaz FR, Gassaway BM, Lee HY, Cartee GD, Philbrick W, Shulman GI, Samuel VT, Bogan JS. Enhanced fasting glucose turnover in mice with disrupted action of TUG protein in skeletal muscle. J Biol Chem. 2013 Jul 12;288(28):20135-50. doi: 10.1074/jbc.M113.458075. Epub 2013 Jun 6. PubMed PMID: 23744065; PubMed Central PMCID: PMC3711282.

1. Dahal GR, Rawson J, Gassaway B, Kwok B, Tong Y, Ptácek LJ, Bates E. An inwardly rectifying K+ channel is required for patterning. Development. 2012 Oct;139(19):3653-64. doi: 10.1242/dev.078592. PubMed PMID: 22949619; PubMed Central PMCID: PMC3436115.