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Chemistry and Biochemistry Labs
Hurst Lab

Publications

Before BYU

21. Hurst, P.J.; Ramsay-Burrough, S.; Jia, Y.; Arens, J.T.; AbdElwakil, M.; McCellan, R.L.; del Castillo, T.J.; Lueckheide, M.; Prabhu, V.M., Waymouth, R.M. The structure and morphology of single-component oligomeric RNA delivery vectors derived from amphiphilic Charge-Altering Releasable Transporters. Under review ACS Nano 2025

20. AbdElwakil, M.M.; Ni, J.; Ramsay-Burrough, S.; Hurst, P.J.; McClellan, R.L; Khasnavis, S.R.; Jia, Y.; Masud, S.R.; Blake T.R.; Sallets, A.; Haabeth, O.A.W.; Sagiv-Barfi, I.; Czerwinski, D.K.; Levy, R.; Wender, P.A.; Kumar, M.E.; Waymouth, R.M. In vivo mRNA delivery to the lung vascular endothelium by dicationic Charge-Altering Releasable Transporters. Under review JACS 2025

19. Driskill, M.M.; Coates, I.A.; Hurst, P.J.; Rajesh, N.U.; Dulay, M.T.; Waymouth, R.M.; Akahata, W.; Matsuda, K.; Smith, J.F.; Jacobson, G.B.; Perry, J.L.; Tian, S.; DeSimone, J.M. Lyophilized SARS-CoV-2 self-amplifying RNA vaccines for microneedle array patch delivery. J. Control. Release. 2025, 384, 113944.

18. Duong, L.; Wu, Y.; Kasallis, S.; Abbondante, S.; Hurst, P.J.; Marshall, M.E.; McCarthy, K.; Reddy, B.; Bru, J.; Perinbam, K.; Pearlman, D.; Patterson, J.P.; Gross, S.P.; Siryaporn, A. Bactericidal activity of mammalian histones is caused by large membrane pore formation. Cell Rep. 2025, 44 (5).

17. Grosvirt-Dramen, A.; Urbach, Z.J.; Hurst, P.J.; Kwok, C.E.; Patterson, J.P.; Wang, F.; Hochbaum, A.I. ACS Nano, 2025, 19 (10), 10162-10172.

16. Pert, E.K.; Hurst, P.J.; Waymouth, R.M.; Rotskoff, G.M. Coacervation drives morphological diversity of mRNA encapsulating nanoparticles. J. Chem. Phys. 2024, 162 (7).

15. Hurst, P.J.; Yoon, J.; Singh, R.; Abouchaleh, M.F.; Stewart, K.A.; Sumerlin B.S.; Patterson, J.P. Hybrid Photoiniferter and Ring-Opening Polymerization Yields One-Pot Anisotropic Nanorods. Macromol. Rapid Comm. 2024, 45 (12), 2400100

14. Dhaoui, R.; Cazarez, S.L.; Xing, L.; Baghdadi, E.; Mulvey, J.T.; Idris, N.S.; Hurst, P.J.; Vena, M.P.; Di Palma, G.; Patterson, J.P. 3D Visualization of Proteins within Metal—Organic Frameworks via Ferritin-Enabled Electron Microscopy. Adv. Funct. Mater. 2024, 34 (13), 2312972

13. Morodo, R.; Dumas, D.M.; Zhang, J.; Lui, K.H.; Hurst, P.J.; Bosio, R.; Campos, L.M.; Park, N.H.; Waymouth, R.M.; Hedrick, J.L. Ring-Opening Polymerization of Cyclic Esters and Carbonates with (Thio) urea/Cyclopropenimine Organocatalytic Systems. ACS Macro Lett. 2024, 13 (2), 181-188

12. Hurst, P.J.; Gassaway, K.J.; Abouchaleh, M.F.; Idris, N.S.; Jones, C.R.; Dicksion, C.A.; Nowick, J.S.; Patterson, J.P. Drug catalyzed polymerization yields one pot nanomedicines. RSC Appl. Polym. 2024, 2 (2), 238-247

11. Hurst, P.J.; Mulvey, J.T.; Bone, R.A.; Selmani, S.; Hudson, R.F.; Guan, Z.; Green, J.R.; Patterson, J.P. CryoEM reveals the complex self-assembly of a chemically driven disulfide hydrogel. Chem. Sci. 2024, 15 (3), 1106-1116

10. Carpenter, B.P.; Rose, B.; Olivas, E.M.; Navarro, M.X.; Talosig, A.R.; Hurst, P.J.; Di Palma, G.; Xing, L.; Guha, R.; Copp, S.M.; Patterson, J.P. The role of protein folding in prenucleation clusters on the activity of enzyme@ metal—organic frameworks. J. Mat. Chem. A. 2024, 12 (2), 813-823

9. Hickey, J.C.; Hurst, P.J.; Patterson, J.P.; Guan, Z. Facile Synthesis of Multifunctional Bioreducible Polymers for mRNA Delivery. Eur. J Chem. 2023, 29 (12), e202203393

8. Barpuzary, D.; Hurst, P.J.; Patterson, J.P.; Guan, Z. Waste-Free Fully Electrically Fueled Dissipative Self-Assembly. J Am Chem Soc 2023, 145 (6), 3727-3735

7. Hurst, P.J.; Graham, A.A.; Patterson, J.P., Gaining structural control by modification of polymerization rate in ring-opening polymerization-induced crystallization-driven self-assembly. ACS Polm. Au 2022, 2 (6), 501-509.

6. Hurst, P.J.; Morris, M.A.; Graham, A.A.; Nowick, J.S.; Patterson, J.P., Visualizing teixobactin supramolecular assemblies and cell wall damage in B. subtilis using CryoEM. ACS Omega 2021, 6 (41), 27412-27417.

5. Ianiro, A.; Hendrix, M. M. R. M.; Hurst, P. J.; Patterson, J. P.; Vis, M.; Sztucki, M.; Esteves, A. C. C.; Tuinier, R., Solvent Selectivity Governs the Emergence of Temperature Responsiveness in Block Copolymer Self-Assembly. Macromolecules 2021, 54 (6), 2912-2920.

4. Hurst, P. J.; Rakowski, A. M.; Patterson, J. P., Ring-opening polymerization-induced crystallization-driven self-assembly of poly-L-lactide-block-polyethylene glycol block copolymers (ROPI-CDSA). Nat Commun 2020, 11 (1), 4690. Highlighted as editor’s choice article.

3. Rizvi, A.; Patel, U.; Ianiro, A.; Hurst, P. J.; Merham, J. G.; Patterson, J. P., Nonionic Block Copolymer Coacervates. Macromolecules 2020, 53 (14), 6078-6086.

2. Carmean, R. N.; Sims, M. B.; Figg, C. A.; Hurst, P. J.; Patterson, J. P.; Sumerlin, B. S., Ultrahigh Molecular Weight Hydrophobic Acrylic and Styrenic Polymers through Organic-Phase Photoiniferter-Mediated Polymerization. ACS Macro Letters 2020, 9 (4), 613-618.

1. Ogata, A. F.; Rakowski, A. M.; Carpenter, B. P.; Fishman, D. A.; Merham, J. G.; Hurst, P. J.; Patterson, J. P., Direct Observation of Amorphous Precursor Phases in the Nucleation of Protein–Metal–Organic Frameworks. J Am Chem Soc 2020, 142 (3), 1433-1442. Featured on the front cover.